Tobacco-specific nitrosamine metabolites are specific to tobacco products; nicotine and its metabolites are also relatively specific but could also come from nicotine replacement therapy products or e-cigarettes. Nicotine can be measured in house dust or silicone wristbands. For more details see Exposure to Tobacco Products.
Biospecimens: Volume requirements - typically up to 3.0 mL of a biospecimen
Core analytes (subset of analytes that will be measured and reported by any targeted HHEAR Lab Hub that provides Tobacco Product analysis in blood, saliva or urine):
| Blood | Saliva | Urine |
|---|---|---|
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|
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Other Tobacco Product analytes (analytes that can also be measured depending on the Lab Hub and the requested analytes) include but are not limited to:
- Cotinine (free) (blood, saliva)
- 4-(methlynitrosamino)-1-(3-pyridyl)-1-butanol (free NNAL) (urine)
- DNA adducts of aromatic amines
- dG-C8 adducts of PhIP, MeIQx, AaC, and IQ
- dG-C8 adduct of 4-ABP
- N6-dA adduct of aristolochic acid-I
Environmental Samples: Volume requirements - one gram of dust or a silicone wristband
- Nicotine