PAH can be analyzed by measurement of well-accepted surrogate compounds in urine that serve as biomarkers for overall PAH exposure. Dust, air, and silicone wristbands are the most common environmental media analyzed, but other media have been used. For more details see Exposure to Polycyclic Aromatic Hydrocarbons (PAH).
Biospecimens: Volume requirements - typically 0.1-3.0 mL of urine
Core analytes (subset of analytes that will be measured and reported by any targeted HHEAR Lab Hub that provides PAH analysis in urine):
- 2-hydroxyfluorene
- 1-hydroxynaphthalene
- 2-hydroxynaphthalene
- 3-hydroxyphenanthrene
- 1-hydroxypyrene
- Phenanthrene tetrol
Other PAH analytes (analytes that can also be measured depending on the Lab Hub and the requested analytes) include but are not limited to:
- Benzo[a]pyrene tetraol
- 1-hydroxybenz[a]anthacene
- 3-hydroxybenzo[c]-phenanthrene
- 1-hydroxychrysene
- 6-hydroxychrysene
- 3-hydroxyfluorene
- 1-hydroxyphenanthrene
- 2-hydroxyphenanthrene
- (2-hydroxyphenanthrene + 3-hydroxyphenanthrene)
- 4-hydroxyphenanthrene
Environmental Samples: Volume requirements - one gram of dust
- Acenapthene
- Anthracene
- Benzo[a]pyrene
- Benzo[b,k,a]fluoranthene
- 1,2 Benzanthracene (Benz[a]anthracene)
- Benzo[e]pyrene
- Chrysene
- Fluoranthene
- Fluorene
- Perylene
- Phenanthrene
- Pyrene