Perfluoroalkyl and Polyfluoroalkyl Substances (PFAS) Analytes

The PFAS most commonly detected in humans include perfluorooctanoic acid (PFOA), perfluorooctane sulfonate (PFOS), perfluorohexane sulfonate (PFHxS), and perfluorononanoic acid (PFNA). Other PFAS may be measured but are detected less frequently. Dust and silicone wristbands are the most common environmental media analyzed. For more details see Exposure to Perfluoroalkyl and Polyfluoroalkyl Substances (PFAS).

Biospecimens: Volume requirements - typically 0.1-1.0 mL of serum or plasma

Core analytes (subset of analytes that will be measured and reported by any targeted HHEAR Lab Hub that provides PFAS analysis in serum or plasma):

  • Perfluorobutanesulfonic acid (PFBS)
  • Perfluorobutanoic acid (PFBA)
  • Perfluorodecanoic acid (PFDA)
  • Perfluoroheptane sulfonic acid (PFHPS)
  • Perfluoroheptanoic acid (PFHPA)
  • Perfluorohexane-1-sulphonic acid (PFHXS)
  • Perfluorohexanoic acid (PFHXA)
  • Perfluorononanoic acid (PFNA)
  • Perfluorooctanesulfonamide (PFOSA)
  • Perfluorooctanesulfonic acid (PFOS)
  • Perfluorooctanoic acid (PFOA)
  • Perfluoro-n-pentanoic acid (PFPEA)
  • Perfluoro-2-propoxyproanoic acid (GenX)
  • Perfluoroundecanoic acid (PFUNDA)

Other PFAS analytes (analytes that can also be measured depending on the Lab Hub and the requested analytes) include but are not limited to:

  • Ethyl Perfluorooctane sulfonamido acetic acid (NETFOSAA)
  • N-methyl Perfluorooctane sulfonamido acetic acid (NMFOSAA)
  • Perfluorodecanesulfonate (PFDS)
  • Perfluorododecanoic acid (PFDODA)

Environmental Samples: Volume requirements - one gram of dust or a silicone wristband

  • Perfluorohexane sulfonate (PFHxS)
  • Perfluorooctane sulfonate (PFOS)
  • Perfluorooctanoic acid (PFOA)
  • Perfluorononanoic acid (PFNA)
  • Sodium bis(1H, 1H,2H,2Hperfluorodecyl) phosphate
  • Sodium bis(1H, 1H,2H,2Hperfluorooctyl) phosphate
  • 2,3,3,3-Tetrafluoro-2(heptafluoropropoxy)propanoic acid (GenX)

Related Links:

Targeted Analyses